this compound is actually only a weak agonist of the androgen receptor (AR), with poor binding. It follows, then, that its value must mostly come from non-AR-mediated effects. It is therefore a Class II steroid. Since it is not very effective in activating ARs, it should be stacked with a Class I steroid that is effective in this regard, such as Primobolan , Deca Durabolin , or trenbolone acetate . There is no point in stacking it with Anadrol®, which has similar activity -- one ought to simply use the more appropriate drug. With testosterone or Deca, Dianabol is to be preferred; with Primobolan or trenbolone acetate, Anadrol® is to be preferred (though Dianabol is still a good choice) because Anadrol® does not aromatize. For an oral-only cycle -- something I don't recommend -- Anadrol® is the better choice in my opinion for that also, at 150 mg/day (preferably divided to 3 or 6 doses.)

Methandrostenolone converts to estradiol via aromatase. The amount of this conversion may be reduced by use of Arimidex , or less preferably Cytadren. Or if the conversion is allowed, Clomid may be used to block adverse estrogenic effects.

Irreversible hoarsening of the voice has been seen in some women from very few tablets of Dianabol: one per day for a few weeks. For this reason, in the 1960s doctors decided to end what had been a fairly common practice of prescribing this drug at one tab per day to women as a "tonic." It is not a good choice for the woman who chooses to use anabolic steroids.

The usual dosing for men is 25-50 mg/day in divided doses, preferably four or five doses. The drug is 17-alkylated and so use should be limited to no more than 6 weeks, and preferably no more than four weeks, with at least an equal amount of time off.

Dianabol Side Effects

As with many other 17aa steroids, Dianabol is also a very weak binder to the Androgen Receptor, so most of it´s effects are thought to be non-receptor mediated, and are attributable to other mechanisms (i.e. protein synthesis as indicated by the production of muscle tissue with very high levels of nitrogen, etc... which was indicated in the 100mg/day study). This also means it only has a modest aromatase activity (2).

Dbol Facts
     [17a-methyl-17b-hydroxy-1,4-androstadien-3-one]
     Molecular Weight: 300.44
     Formula: C20H28O2
     Melting Point: N/A
     Manufacturer: Ciba (originally)
     Release Date: 1956
     Effective dose: 25-50mgs (as low as 10 and as high as 100 have been reported)
     Active Life: 6-8hours
     Detection Time: up to 6 weeks
     Anabolic/Androgenic Ratio (Range): 90-210:40-60